There are 2 solutions. The longest is PLASM with 5 letters, and the shortest is ZOA with 3 letters.
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No - clue "ENDING WITH PROTO-" is not trending right now. Today´s hot clues are: Hit, hypnosis, Very energetic, refuge and the branch of mechanics concerned with motion without reference to force or mass.
Solutions are between 3 and 5 letters long.