The clue "Issue that one may 49-Down" last appeared in the USA Today crossword on July 4, 2017. The correct answer for this puzzle is "NIT", a 3-letter word.
Solution NIT is 3 letters long. So far we haven´t got a solution of the same word length.
There is 1 solutions. The longest is NIT with 3 letters, and the shortest is NIT with 3 letters.
No, "ISSUE THAT ONE MAY 49-DOWN" hasn´t seen a spike right now. Solvers are most interested in: BRIBABLE, ___ la Douce, Spotted rodent, esculent and Police officer.
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The solution is 3 letters long.