The clue "Major blood vessel" last appeared in the Newsday crossword on November 19, 2025. The correct answer for this puzzle is "AORTA", a 5-letter word.
Solution AORTA is our most searched for solution by our visitors. Solution AORTA is 5 letters long. We have 0 further solutions of the same word length.
There are 2 solutions. The longest is ARTERY with 6 letters, and the shortest is AORTA with 5 letters.
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Solutions are between 5 and 6 letters long.