The clue "Reply to 5-Down" last appeared in the New York Times crossword on December 11, 2016. The correct answer for this puzzle is "ITIS", a 4-letter word.
Solution ITIS is 4 letters long. So far we haven´t got a solution of the same word length.
There is 1 solutions. The longest is ITIS with 4 letters, and the shortest is ITIS with 4 letters.
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The solution is 4 letters long.